ea0049ep595 | Diabetes therapy | ECE2017
Bozek Tomislav
, Blazekovic Antonela
, Perkovic Matea Nikolac
, Gotovac Kristina
, Smircic-Duvnjak Lea
, Pivac Nela
, Borovecki Fran
Introduction: Growing evidence suggests that nutrients and hormonal signals converge and directly act on brain centers, leading to changes in energy metabolism and stable body weight over time. Catechol O-methyltransferase (COMT) is one of the major enzymes involved in catecholamine and estrogen degradation. There is a well-established association between the COMT Val108/158Met polymorphism and abdominal obesity, blood pressure increase and T2DM. Basal insulin detemir besides ...